iPSC based-Dry AMD model using 3D-Bioprinted Choroid and RPE Cells
Time: 2:00 pm
day: Preclinical PM - Day 1
Details:
- Differentiation overview of human iPSC derived-endothelial cells, pericytes, fibroblasts and RPE cells.
- 3D bioprinting technology to generate highly vascularized choroid tissue and maturation into choroid/RPE combination of outer blood retinal barrier (oBRB) model.
- Investigation of dry-AMD phenotype using alternative pathway of complement system and complement factor H-knockout iPSC derivatives.