Roundtable Discussion: Overcoming Discovery, Preclinical & Clinical Challenges at Each Stage of Drug Development for Dry AMD & Geographic Atrophy

Time: 1:45 pm
day: Conference Day 1


  • Discovery: What are the latest innovations being utilized (including imaging, tissue culture and organoid studies) to improve disease knowledge and therefore fast-track drug development? What are the new targets and drug modalities beyond complement and inflammasome systems?
  • Translational: What are the preclinical models (in vitro, in vivo and ex vivo) being developed to ensure more accurate replication of disease for smoother translation into the clinic? What are the current safety and efficacy models and how can they be improved?
  • Clinical: What are the current FDA-approved clinical endpoints and what are the new functional endpoints required to show efficacy to the EMA? How can these endpoints be achieved in niche clinical trials for dry AMD vs GA?

Moderator Feedback & Audience Debate:

Moderators will be assigned to each roundtable to facilitate discussion and collate the findings. Following the roundtable discussions, they will present back to the entire delegation and open up a wider audience debate