Optimize Macrophage Modulation for Late Nonexudative Dry AMD

Time: 12:15 pm
day: Track 1 Day 1 AM


  • Examine how macrophages play a critical role in the response to tissue stress and are highly “plastic” in their behaviour
  • Explore the dampening of the pro-inflammatory M1 response reduces down-stream mediators including cytokines, complement and the inflammasome
  • Analyze transcriptional modulation with TMi-018 dose-dependently reduces GA-like onset & expansion in pre-clinical testing
  • Showcasing how as a small molecule, TMi-018 is demonstrated suitable for extended delivery